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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK2
All Species:
28.48
Human Site:
Y139
Identified Species:
52.22
UniProt:
Q13177
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13177
NP_002568.2
524
58043
Y139
S
N
T
V
K
Q
K
Y
L
S
F
T
P
P
E
Chimpanzee
Pan troglodytes
XP_516976
524
58004
Y139
S
N
T
V
K
Q
K
Y
L
S
F
T
P
P
E
Rhesus Macaque
Macaca mulatta
XP_001099936
524
57950
Y139
S
N
T
V
K
Q
K
Y
L
S
F
T
P
P
E
Dog
Lupus familis
XP_849432
524
57951
Y139
S
N
T
V
K
Q
K
Y
L
S
F
T
P
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIN4
524
57912
Y139
S
N
T
V
K
Q
K
Y
L
S
F
T
P
P
E
Rat
Rattus norvegicus
Q64303
524
57942
Y139
S
N
T
V
K
Q
K
Y
L
S
F
T
P
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422671
521
57527
Y136
K
D
T
A
K
Q
K
Y
L
S
F
S
A
P
E
Frog
Xenopus laevis
NP_001083738
517
57265
S134
T
D
K
Q
K
Y
L
S
F
S
A
P
D
K
D
Zebra Danio
Brachydanio rerio
NP_001020627
539
59696
G154
E
K
D
S
F
P
S
G
E
Q
S
P
A
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
N258
S
N
H
S
H
T
N
N
G
N
S
G
G
S
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
S185
P
M
T
T
S
T
S
S
A
G
Y
N
S
K
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
P510
P
L
K
Q
T
H
A
P
T
T
P
N
R
T
S
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
L564
S
P
V
Q
A
S
P
L
H
P
I
A
T
A
N
Conservation
Percent
Protein Identity:
100
99.6
99
96.7
N.A.
97.1
96.9
N.A.
N.A.
92.7
87.2
83.8
N.A.
34.4
N.A.
53.3
N.A.
Protein Similarity:
100
99.6
99.2
98.2
N.A.
98.4
98.2
N.A.
N.A.
95.6
92.5
89
N.A.
50.5
N.A.
68.5
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
66.6
13.3
0
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
80
33.3
6.6
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32
32.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.4
42.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
8
0
8
0
8
8
16
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
8
0
0
0
0
0
0
0
0
0
8
0
8
% D
% Glu:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
54
% E
% Phe:
0
0
0
0
8
0
0
0
8
0
54
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
8
8
0
8
8
0
0
% G
% His:
0
0
8
0
8
8
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
8
8
16
0
62
0
54
0
0
0
0
0
0
24
8
% K
% Leu:
0
8
0
0
0
0
8
8
54
0
0
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
54
0
0
0
0
8
8
0
8
0
16
0
0
8
% N
% Pro:
16
8
0
0
0
8
8
8
0
8
8
16
47
47
0
% P
% Gln:
0
0
0
24
0
54
0
0
0
8
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
62
0
0
16
8
8
16
16
0
62
16
8
8
8
8
% S
% Thr:
8
0
62
8
8
16
0
0
8
8
0
47
8
16
0
% T
% Val:
0
0
8
47
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
54
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _